Audentes is one of the leaders in the nascent field of gene therapy, using an adeno-associated virus, or AAV, vector to carry a healthy copy of a gene into a cell. The viral vectors essentially are vehicles, modified so they aren't infectious but can slip past a cell's normal defenses to deliver the healthy gene.
Audentes sold 5 million shares at $15 apiece in its IPO. The $75 million raise will help Audentes fund clinical work it’s doing on rare diseases such as X-Linked myotubular myopathy, Crigler-Najjar Syndrome, and Pompe disease.

Audentes Therapeutics, Inc. is an early-stage biotechnology company. The Company is focused on developing and commercializing gene therapy products for patients suffering from serious, life-threatening rare diseases caused by single gene defects. The Company has a portfolio of product candidates, including AT132 for the treatment of X-Linked Myotubular Myopathy (XLMTM); AT342 for the treatment of Crigler-Najjar Syndrome (Crigler-Najjar); AT982 for the treatment of Pompe disease, and AT307 for the treatment of the CASQ2 subtype of Catecholaminergic Polymorphic Ventricular Tachycardia (CASQ2-CPVT). The Company's subsidiary is Audentes Therapeutics UK Ltd. As of September 30, 2016, the Company had not generated any revenues.
Key stats and ratios
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Net profit margin | - | - |
Operating margin | - | - |
EBITD margin | - | - |
Return on average assets | -58.78% | -45.98% |
Return on average equity | -68.94% | -139.89% |
Employees | 97 |